Research
Molecular Mechanisms of Paramyxovirus Replication and Pathogenicity
We study disease-causing mechanisms by searching for host factors required for paramyxoviruses such as measles virus and mumps virus to multiply in cells and by clarifying their interactions with factors on the viral side.
Mechanism of Activation of Respiratory Viruses by Host Proteases
Many viruses have protein spikes (spike proteins) on the surface of their particles. We have shown that the spike proteins of various respiratory viruses are activated by a protease called TMPRSS2 in host cells.
Research on the Development of Viral Vectors and their Application to Advanced medicine
Paramyxoviruses are used as viral vectors for gene therapy, cancer therapy, and vaccine development. We are conducting research on the development of various viral vectors for clinical applications.We are willing to accept collaborations and other research projects.